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學院教職員

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彭也教授

Prof. Ye PENG

PhD Microbiome Science (HKU), MSc Biochemistry & Molecular Biology (SCUT), BEng Biopharmaceutical Engineering (SCUT)

研究助理教授

電郵: yepeng@cuhk.edu.hk

 

ORCID: 0000-0003-3791-2305

Scopus Author ID: 57218526006

學術委任

  • Cellular and Molecular Life Sciences編輯

  • Biomedicines客座編輯

  • Frontiers in Microbiomes審稿編輯

  • Fleming Fund Fellowships導師

個人簡介

彭也博士是一位專注於腸道微生物群在早期生命健康與疾病中角色的微生物群科學家。他在香港大學完成博士學位，並在香港中文大學接受博士後培訓，他的隊列研究揭示了圍產期暴露如何塑造腸道微生物群的發展並影響兒童肥胖、食物敏感，對疫苗的免疫反應以及對抗抗生素耐藥性細菌的定植抵抗力。彭博士的跨學科研究結合了多組學、流行病學和機器學習，以推進微生物群科學並抗擊抗生素耐藥性。他的長期願景是明確定義「健康的微生物群」，並將發現轉化為個性化療法，以改善從兒童到老齡人口的健康。

研究方向

  • 微生物組在健康與疾病中作用的多組學研究

  • 開發微生物組及抗菌素抗藥性相關的科學研究工具

部份學術文章

  1. Peng Y*, Zhu J*, Wang S*, Liu Y*, Liu X, DeLeon O, Zhu W, Xu Z, Zhang X, Zhao S, Liang S, Li H, Ho B, Ching JY, Cheung CP, Leung TF, Tam WH, Leung TY, Chang EB, Chan FKL, Zhang L#, Ng SC#, Tun HM#. A metagenome-assembled genome inventory for children reveals early-life gut bacteriome and virome dynamics. Cell Host Microbe. 2024 Dec 11;32(12):2212-2230.e8.

  2. Peng Y*, Tun HM*#, Ng SC, Wai HK, Zhang X, Parks J, Field CJ, Mandhane P, Moraes TJ, Simons E, Turvey SE, Subbarao P, Brook JR, Takaro TK, Scott JA, Chan FK, Kozyrskyj AL#. Maternal smoking during pregnancy increases the risk of gut microbiome-associated childhood overweight and obesity. Gut Microbes. 2024 Jan-Dec;16(1):2323234.

  3. Tun HM*, Peng Y*, Massimino L, Sin ZY, Parigi TL, Facoetti A, Rahman S, Danese S, Ungaro F#. Gut virome in inflammatory bowel disease and beyond. Gut. 2024 Jan 5;73(2):350-360.

  4. Peng Y*, Zhang L*, Mok CKP, Ching JYL, Zhao S, Wong MKL, Zhu J, Chen C, Wang S, Yan S, Qin B, Liu Y, Zhang X, Cheung CP, Cheong PK, Ip KL, Fung ACH, Wong KKY, Hui DSC, Chan FKL, Ng SC#, Tun HM#. Baseline gut microbiota and metabolome predict durable immunogenicity to SARS-CoV-2 vaccines. Signal Transduct Target Ther. 2023 Sep 25;8(1):373.

  5. Peng Y*, Chiu ATG*, Li VWY*, Zhang X, Yeung WL, Chan SHS#, Tun HM#. The role of the gut-microbiome-brain axis in metabolic remodeling amongst children with cerebral palsy and epilepsy. Front Neurol. 2023 Feb 27;14:1109469.

  6. Ng SC*, Peng Y*, Zhang L*, Mok CK, Zhao S, Li A, Ching JY, Liu Y, Yan S, Chan DLS, Zhu J, Chen C, Fung AC, Wong KK, Hui DS, Chan FK#, Tun HM#. Gut microbiota composition is associated with SARS-CoV-2 vaccine immunogenicity and adverse events. Gut. 2022 Jun;71(6):1106-1116.

  7. Peng Y*, Zhang D*, Chen T, Xia Y, Wu P, Seto WK, Kozyrskyj AL, Cowling BJ, Zhao J, Tun HM#. Gut microbiome and resistome changes during the first wave of the COVID-19 pandemic in comparison with pre-pandemic travel-related changes. J Travel Med. 2021 Oct 11;28(7):taab067.

  8. Tun HM*#, Peng Y*, Chen B, Konya TB, Morales-Lizcano NP, Chari R, Field CJ, Guttman DS, Becker AB, Mandhane PJ, Moraes TJ, Sears MR, Turvey SE, Subbarao P, Simons E, Scott JA, Kozyrskyj AL#. Ethnicity Associations With Food Sensitization Are Mediated by Gut Microbiota Development in the First Year of Life. Gastroenterology. 2021 Jul;161(1):94-106.

  9. Peng Y*, Liang S*, Poonsuk K*, On H, Li SW, Maurin MMP, Chan CH, Chan CL, Sin ZY, Tun HM#. Role of gut microbiota in travel-related acquisition of extended spectrum β-lactamase-producing Enterobacteriaceae. J Travel Med. 2021 Apr 14;28(3):taab022.

  10. Peng Y*, Tang S*, Wang D*, Zhong H, Jia H, Cai X, Zhang Z, Xiao M, Yang H, Wang J, Kristiansen K, Xu X, Li J#. MetaPGN: a pipeline for construction and graphical visualization of annotated pangenome networks. Gigascience. 2018 Nov 1;7(11):giy121.

Last Updated: 12 March 2025

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