Prof. Martin Chi-sang WONG
黃至生教授

Prof. Martin Chi-sang WONG
BMedSc (Hons), MSc (Hons), MBChB, MD (CUHK), MPH, MBA, FRACGP, FRSPH, FHKCFP, FHKCCHP, FHKAM (Family Medicine), DCH (Ire), FESC, FACC, FAcadTM, FFPH, FHKAN (Hons), FRCP (Glasgow), FRCP (Edinburgh)
Professor
wong_martin@cuhk.edu.hk

Research Links

Academic Appointments

  • Professor, JC School of Public Health and Primary Care, The Faculty of Medicine
  • Director, The Centre for Health Education and Health Promotion, The Faculty of Medicine
  • Professor (by courtesy), Department of Sports Science and Physical Education, The Chinese University of Hong Kong
  • Adjunct Professor of Global Health, School of Public Health, Peking University
  • Adjunct Professor, School of Public Health, Peking Union Medical College
  • Adjunct Professor, School of Public Health, Fudan University
  • Chairman, Grant Review Board, Health Care and Medical Research Fund, Food and Health Bureau, HKSAR Government
  • Consultant (Honorary), Department of Family Medicine, NTEC, Hospital Authority
  • Editor-in-Chief, Hong Kong Medical Journal, Hong Kong Academy of Medicine

Bio

(1). Personal and Professional Achievements

Professor Wong is a scholar and specialist in Family Medicine, and a researcher in the field of cancer screening and prevention of chronic diseases. He is currently a Professor and Director of the Centre for Health Education and Health Promotion, Faculty of Medicine, the Chinese University of Hong Kong. He is also the Associate Head and Dean of Students of the United College, CUHK. He has over 600 publications in international peer-reviewed journals, and has received over 15 international and local research awards for his studies. His expertise of “Colorectal Neoplasm”, “Mass Screening”, “Early Detection of Cancer” ranks in the top 0.055%, 0.095%, and 0.14% in the world, respectively. He ranks as the top number 1 researcher in China in the field of disease screening [from expertscape: https://www.expertscape.com/; on 10/9/2022]. He is a leader of an international research group which is a global organization jointly participated by various Universities in the world. He has been co-chairman of the APRU Global Programme [NCD] for many years. In 2024, he was selected as a “Highly Cited Researcher” by Clarivate, an award which recognizes awardees as the pioneer in his field over the last decade, demonstrating significant and broad influence in one’s field of research.

He is currently the Chairman of the Association of the Pacific Rim Universities, NCD stream; Co-Chairman of the Grant Review Board, Health and Medical Research Fund, the Health Bureau; a member of the Medical Council of Hong Kong and its Education and Accreditation Committee; Editor-in-Chief in the Hong Kong Academy of Medicine; Convener of the Advisory Group on Hong Kong Reference Framework for Care of Diabetes and Hypertension in Primary Care Settings; Convener of the Advisory Group on Hong Kong Reference Framework for Preventive Care for Older Adults in Primary Care Settings; Convener of the Advisory Group on Hong Kong Reference Framework for Preventive Care for Children in Primary Care Settings ; Convener of Hong Kong Reference Framework for Life Course Preventive Care in Primary Healthcare; Convenor of the Hong Kong Reference Framework for common musculoskeletal problems; a member of the Expert Advisory Panel in Implementation Science of the Hong Kong SAR Government, a member of the Research Council of the Food and Health Bureau, and a member of the Health Promoting School Advisory Committee.

He is a reviewer of the Medical Research Council, United Kingdom; expert reviewer of the National Medical Research Council, Singapore; external examiners of doctoral thesis in the University of Malaya; and an external reviewer of the Public Policy Research Funding Scheme, Research Grant Council of Hong Kong. His enthusiasm to teaching has been well received by students and has been selected for the “Master Teacher” and the “Annual Teacher of the Year Award” for 7 years.

In 2016, he was conferred an Honorary Fellow by the Hong Kong Academy of Nursing to recognise his achievements in the profession and contributions to primary care. He has served as Editor of the Hong Kong Academy of Medicine since December 2016; a Fellow of the American College of Cardiology; a Fellow of the European Society of Cardiology; a Fellow and expert panel of the Academy of Translational Medicine, European Society of Translational Medicine; a Fellow of the Faculty of Public Health in 2018; and a Fellow of the Royal College of Physicians in 2019. He was appointed as an Adjunct Professor of Peking Union Medical College in March 2019; Adjunct Professor of Global Health by Peking University; and Adjunct Professor of Public Health, Fudan University.

(2). Contribution to charitable activities

Prof. Wong has participated in community services for more than 30 years.  He has been Chairman/ Director/ Board member or honorary consultants of more than 50 NGOs in the medical and social welfare sector, mainly working with the chronically disabled, marginalized youth, rehabilitated offenders and other underprivileged groups.  He joined the Regeneration Society in 1999, which has a major mission and vision to serve the chronically ill.  He subsequently took up the position of the Chairmen of its steering committee and executive committee, and was elected as the Chairman of its board of directors.  He is the Chairman of the organizing committee for the Hong Kong-wide Ten Warriors of Regeneration Selection for 10 consecutive years which recognizes the brilliant achievements and resilience of the chronically disabled.  Under his leadership the Society was awarded several major grants including funding from the Community Chest and commercial corporations like the Hang Seng Bank for projects serving the chronically ill.  He aims to bring commercial involvements into social services and promote the concept of caring organizations.  During his past 20 years of voluntary service, he has delivered more than 500 health talks in the community to raise the awareness of chronic diseases.  Owing to his community contributions, he was awarded the First Outstanding Volunteer Award by the Agency for Volunteer Service in 2005, the Hong Kong Humanity Award by the HK Red Cross in 2009, the Award of Benevolence by The Hong Kong Macau Taiwanese Charity Fund in 2010, the Outstanding NGO Volunteer Award by the Correctional Services Department in 2011, and the 15th Fervent Global Love of Lives, 2012 medal, by the Chou Ta-kuan Cultural and Educational Foundation, which has been recognized by international media as “The Nobel of Life”.  He was selected as an awardee of the “Ten Outstanding Young Persons” by the JCI Hong Kong in 2012. In 2018, he was awarded the “1st Distinguished Research Making Family Medicine Shine Award” organized by the World Organization of Family Doctors (WONCA) to recognize his excellent contributions to the global population.

(3) Contribution to boards/committees, public body or voluntary service

Professor Wong has contributed to more than 60 Governmental boards/committees and community organizations in his past >30 years of volunteer services as listed in section 11 above. Professor Wong has performed research work in the community for more than 20 years and his research findings have contributed to the launch of the “colorectal cancer screening pilot programmes” by the Department of Health, which has been regularised into one covering all eligible citizens aged 50 to 75 years. This could substantially reduce the burden of diseases; saves life; and improve healthcare in Hong Kong.

 

Research Interest

  • Disease Screening and Prevention
  • Control of Non-Communicable Diseases
  • Organization of Primary Care

Recent Funded Research Projects

Competitive Research Grants

    • Enhancing Patient Experience and Healthcare Journey in the Public Sector in Hong Kong: A Mixed Qualitative and Quantitative Study of the “HA Go” Application. Public Policy Research Funding Scheme, The Chief Executive Policy Unit [PI]
    • Screening Programme for Osteoporosis in Hong Kong: A Mixed Qualitative and Quantitative Study with Cost-effectiveness Analysis. Public Policy Research Funding Scheme, The Chief Executive Policy Unit [PI]
    • Evaluation of the Utilisation of the Hong Kong Reference Framework for Preventive Care for Children in Primary Care Settings: a mixed method study. Health Bureau – Health and Medical Research Fund (HMRF) [PI]
    • Promoting self-management behaviours among older adults with diabetes mellitus by integrating Just-In-Time adaptive interventions in mobile health applications: A randomized controlled trial. Health Bureau – Health and Medical Research Fellowship Scheme [PI]
    • Education and Promotion of Weight Control in School Children of Hong Kong. Knowledge Transfer Project Fund (KPF) 2022/23 [PI]
    • Evaluation of the Adoption of the Hong Kong Reference Framework for Preventive Care for Older Adults in Primary Care Settings: a mixed method approach. Food and Health Bureau – Health and Medical Research Fund (HMRF) [PI]
    • Promoting Physical Activity Among Primary School Children and Their Families in Hong Kong: A Community-based Healthy Lifestyle Program (“F.I.T. Family”). Research Grants Council – Research Impact Fund (RIF) Scheme [Co-PI]

 

    • The risk of advanced neoplasia within subcentimetric polyps detected in colorectal cancer screening participants in Chinese populations: a multi-centre colonoscopy study. Research Grants Council (RGC), General Research Fund (GRF) [PI]
    • The risk of advanced colorectal neoplasia according to the length of the period of surveillance colonoscopy: a multi-centre colonoscopy trial. Research Grants Council (RGC), General Research Fund (GRF) [PI]
    • Validation of a scoring system to predict the risk of advanced proximal neoplasia for colorectal cancer screening: a multi-centre study in 13 Asia Pacific countries/ regions. Research Grants Council (RGC), General Research Fund (GRF) [PI]
    • Recurrence rates in high-risk subjects with baseline advanced colorectal adenomas followed up at different surveillance intervals: a multi-centre randomised controlled trial in four Chinese cities. Food and Health Bureau (FHB), Health and Medical Research Fund (HMRF) [PI]
    • Adoption of a drug adherence-enhancing application to achieve optimal medication adherence and blood pressure control among hypertensive patients: a community-based intervention programme. Food and Health Bureau (FHB), Health Care and Promotion Scheme (HCPS), Health and Medical Research Fund (HMRF) [PI]
    • Evaluation of the Introduction of the Reference Framework for Diabetes among Primary Care Physicians in Primary Care Settings. Food and Health Bureau (FHB), Health and Medical Research Fund (HMRF) [PI]
    • Evaluation of Dietary Intervention Models for Management of Stage I Hypertensive Patients in a Primary Care Setting: Randomized Controlled Clinical Trial. Food and Health Bureau (FHB), Health and Medical Research Fund (HMRF) [PI]
    • Post-polypectomy Surveillance Interval In High-risk Subjects After Screening Colonoscopy. Research Grants Council (RGC), General Research Fund (GRF) [Co-I]
    • A Feasibility Study on A Healthcare Voucher Scheme for Screening and Management of Cardiovascular Risk Factors Associated Chronic Diseases in the General Population: A Mixed Methods Evaluation. Public Policy Research Funding Scheme [Co-I]
    • Continuous Glucose Monitoring as an Adjunct to Lifestyle Modification in Individuals with Impaired Glucose Tolerance: A Randomised Controlled Trial. Food and Health Bureau (FHB), Health and Medical Research Fund (HMRF) [Co-I]
    • A Randomized Controlled Trial Evaluating an Online Intervention Based on the Trans-theoretical Model in Increasing Seasonal Influenza Vaccination among Community-dwelling People Aged 65 Years. Food and Health Bureau (FHB), Health and Medical Research Fund (HMRF) [Co-I]
    • A Randomized Controlled Trial Evaluating Two E-health Interventions (Presence/Absence of Motivational Interviewing) in Increasing Colorectal Cancer Screening among People Aged 50-60 with Moderate Risk. Food and Health Bureau (FHB), Health and Medical Research Fund (HMRF) [Co-I]
    • WHO-2025 Target to Reduce Children and Youth Physical Inactivity: Impact of Training Workshops and Evidence-based Electronic Portal for Educators (TWEEET). Knowledge Transfer Project Fund (KPF) [Co-I]
    • Retinal risk factors for stroke and coronary heart disease in patients with type 2 diabetes – Are they different? Research Grants Council (RGC), General Research Fund (GRF) [Co-I]
    • Community-driven Social Media Campaigns for Promoting Organ Donation Registration in Hong Kong. Food and Health Bureau (FHB), Health Care and Promotion Scheme (HCPS) [Co-I]
    • A prospective colonoscopic study to investigate risk of colorectal neoplasms in first-degree relatives of patients with non-advanced adenomas. Food and Health Bureau (FHB), Health and Medical Research Fund (HMRF) [Co-I]
    • Pocket-size Mobile Echocardiographic Device Screening for Thoracic Aortic Aneurysm in Chinese Hypertensive Patients. Food and Health Bureau (FHB) – Health and Medical Research Fund (HMRF) [Co-I]
    • Providing Repeat Prescriptions for Patients with Controlled Hypertension – A Randomized Controlled Trial. Food and Health Bureau (FHB) – Health and Medical Research Fund (HMRF) [Co-I]
    • Projection of All-cause Mortality and Life-expectancy in Hong Kong to 2041 by Socio-economic Status: A Population-based Retrospective Cohort Study. Food and Health Bureau *FHB) – Health and Medical Research Fund (HMRF) [Co-I]
    • A Randomized Controlled Trial Evaluating Efficacy of an Intervention Which Enhances Social Support and Positive Affect through Online Social Networking in Smoking Cessations. Food and Health Bureau (FHB) – Health and Medical Research Fund (HMRF) [Co-I]
    • Promoting Physical and Health Literacy in Hong Kong Pre-school Teachers, Children and their Families. Knowledge Transfer Project Fund [Co-I]
    • A Model of Knowledge Translation: The Active Healthy Kids Report Card on Physical Activity for Hong Kong Youth. Knowledge Transfer Project Fund [Co-I]
    • “Love Others Like Ourselves-Pass Life to Others” – A Social Marketing Program to Promote Organ Donation among Protestant and Roman Catholic Churches Goes and Their Significant Others. Food and Health Bureau (FHB), Health Care and Promotion Scheme (HCPS) [Co-I]
    • Trends and Implications of Poverty and Social Disadvantages in Hong Kong: A Multi-disciplinary and Longitudinal Study. Research Grants Council (RGC), Strategic Public Policy Research [Co-I]
    • A Community-based, Theory-based, Setting-based Screening and Clustered Randomised Controlled Trial to Promote Physical Activity among Physically Inactive People with Impaired Glucose Tolerance and Impaired Fasting Glucose. Food and Health Bureau (FHB), Health and Medical Research Fund (HMRF) [Co-I]
    • Propose and Evaluate New Cholesterol Screening Model for Cardiovascular Disease Primary Prevention in Chinese and Foreign Population – Modeling Study. National Natural Science Foundation [Co-I]
    • Shenzhen Municipal Key Laboratory for Health Risk Analysis. Science & Technology Innovation Commission of SZ Municipality – SZ Municipal Science & Technology Programme [Co-I]
    • Electroacupuncture and Wrist Splinting for Carpal Tunnel Syndrome: A Randomized Trial Primary Care Setting. Food and Health Bureau (FHB), Health and Health Services Research Fund (HHSRF) [Co-I]
    • A Randomized, Controlled Clinical Trial: The Effects of Mindfulness-based Cognitive Therapy on Chronic Insomnia among Chinese Patients in the Community. Food and Health Bureau (FHB), Health and Health Services Research Fund (HHSRF) [Co-I]
    • Smoking HPV Infection and P53 Mutation as Etiological and Prognostic Factors in Oropharyngeal Cancer – A Case Control Study. Food and Health Bureau (FHB), Research Fund for the Control of Infectious Diseases (RFCID) [Co-I]
    • Using a Systematic Approach to Evaluate Primary Care Development in Hong Kong, Shenzhen, Shanghai. Research Grants Council (RGC), Strategic Public Policy Research (SPPR) [Co-I]
    • Smoking, HPV Infection and P53 Mutation as Etiological and Prognostic Factors in Oropharyngeal Cancer – A Case Control Study. Food and Health Bureau (FHB), Research Fund for the Control of Infectious Diseases (RFCID) [Co-I]
    • The Public Health Impacts of the Policy Decision to Reduce Alcohol Tax in Hong Kong. Research Grants Council (RGC), Public Policy Research Funding Scheme [Co-I]
    • The Association of Human Papillomavirus (HPV) Infection in Occurrence and Prognosis of Head and Neck Cancer – A Case Control and Cohort Study. Hong Kong Anti-Cancer Society [Co-I]
    • A Systematic Review of Molecular Biomarkers Predicting Clinical Outcomes of Wild-type KRAS Metastatic Colorectal Cancer Treated with Anti-EGFR Monoclonal Antibodies. Food and Health Bureau (FHB), Health and Health Services Research Fund (HHSRF) [Co-I]

​​

Non-Competitive Research Grants

    • Screening for Chronic Obstructive Pulmonary Disease [COPD] in Primary Care. CUHK Research Committee Funding (Direct Grants) [PI]
    • Modulation of gut microbiota to enhance health and immunity in vulnerable individuals during COVID-19 pandemic. Food and Health Bureau – Commissioned Studies [PI]
    • Novel strategies to facilitate early detection, prevention and Intervention for long-Term Health problems related to COVID-19 (NovITor-COVID study). Food and Health Bureau – Commissioned Studies [Co-PI]
    • Global Epidemiology of Metabolic Syndrome: A Systematic Review and Meta-analysis. CUHK Research Committee Funding (Direct Grants) [PI]
    • Comparative cost-effectiveness analysis of different pneumococcal vaccination strategies in the community. CUHK Research Committee Funding (Direct Grants) [PI]
    • Mixed method evaluation of pneumococcal vaccination strategy for older adults in Hong Kong. Food and Health Bureau – Commissioned Studies [PI]

 

    • Practice of screening for chronic diseases among Hong Kong residents: a population-based survey. Lee Hysan Foundation Research Grant and Endowment Fund Research Grant Scheme [PI]
    • The Persistence, Clearance and Acquisition of Oral Human Papillomavirus Infection in the General Population: a Prospective Cohort Study. FHB Commissioned Study [PI]
    • Epidemiology of Human Papillomavirus (HPV) Infection among HPV-vaccinated Young Adult Female in Hong Kong FHB Commissioned Study [PI]
    • Epidemiology of oral HPV infection in the general population in Hong Kong: baseline data before implementation of HPV-based screening and vaccination programmes. FHB Commissioned Study [PI]
    • Evaluation of the Colorectal Cancer Screening Pilot Programme in Hong Kong: Awareness, Knowledge, Attitude, Perception, Practice and Satisfaction of Stakeholders. FHB Commissioned Study [Co-I]
    • Molecular Epidemiology of Human Papillomavirus (HPV) Infection in Hong Kong Women with Cervical Cytological Abnormalities. FHB Commissioned Study [Co-I]
    • Prevalence and Associated Factors of Parental Acceptability of Universal Free and Paid HPV Vaccination for 9-13 Years Old Chinese Boys and Girls in Hong Kong. FHB Commissioned Study [Co-I]
    • A Pilot Study of Gut Microbiota Composition and Hypertension in the Hong Kong Chinese Population. FHB Commissioned Study [Co-I].
    • Extended Evaluation of Stakeholder Satisfaction of Chronic Disease Management and Family Medicine Training Programmes of the Hospital Authority. FHB Commissioned Study [Co-I]
    • Enhancing Professional Knowledge of Primary Care Doctors with Practical Evidence-based Guide to Improve Patient Care in the Community. Commerce and Economic Development Bureau, Professional Services Development Assistance Scheme [Co-I]

Selected Publications

  1. Martin CS Wong, Harry H.X. Wang, Mandy W.M. Kwan, et al. Dietary counselling has no effect on cardiovascular risk factors among Chinese Grade 1 hypertensive patients: a randomized controlled trial. European Heart Journal 2015;36:2598-2607 (Original Research; Impact Factor: 22.673, rank: 2/138 in Cardiac and Cardiovascular System)
  2. Martin CS Wong, Thomas YT Lam, Kelvin FK Tsoi et al. A validated tool to predict colorectal neoplasia and inform screening choice for asymptomatic subjects. Gut 2014;63:1130-1136 (Original Research; Impact Factor: 19.819, rank: 3/88 in Gastroenterology and Hepatology)
  3. Martin CS Wong, Jessica YL Ching, Siew C Ng et al. Prediction of proximal advanced neoplasia: a comparison of four existing sigmoidoscopy-based strategies in a Chinese population. Gut 2015;64:776-783 (Original Research; Impact Factor: 19.819, rank: 3/88 in Gastroenterology and Hepatology)
  4. Martin CS Wong, William B. Goggins, Harry H.X. Wang, et al. Global Incidence and Mortality for Prostate Cancer: Analysis of Temporal Patterns and Trends in 36 Countries. European Urology 2016;70: 862-874 (Original Research; Impact Factor: 17.947, rank: 2/85 in Urology and Nephrology)
  5. Martin CS Wong, Jessica YL Ching, Victor CW Chan et al. Informed choice vs. no choice in colorectal cancer screening tests: a prospective cohort study in real-life screening practice. Am J Gastroenterol 2014;109:1072-1079 (Original Research; Impact Factor: 10.171, rank: 7/88 in Gastroenterology and Hepatology)
  6. Martin CS Wong, Jessica YL Ching, Han-mo Chiu et al. Risk of colorectal neoplasia in individuals with self-reported family history: a prospective colonoscopy study from 16 Asia-Pacific regions. Am J Gastroenterol 2016;111:1621-1629 (Original Research; Impact Factor: 10.171, rank: 7/88 in Gastroenterology and Hepatology)
  7. Martin CS Wong, Jason L.W. Huang, Jacob George, Junjie Huang, Colette Leung, Mohammed Eslam, Henry L.Y. Chan, Siew C. Ng. The changing epidemiology of liver diseases in the Asia-Pacific region. Nat. Rev. Gastroenterol. Hepatol. 2019;16:57-73 (Review Article; Impact Factor: 29.848 rank: 1/88 in Gastroenterology and Hepatology)
  8. Martin CS Wong, Junjie Huang, Jason LW Huang, Tiffany WY Pang, Peter Choi, Jingxuan Wang, Jason Chiang, Johnny Yu Jiang. Global Prevalence of Colorectal Neoplasia: a Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol 2020;18:553-561. (Original Research; Impact Factor: 11.382, rank: 8/92 in Gastroenterology and Hepatology)
  1. Martin CS Wong, Junjie Huang, Veeleah Lok, Jingxuan Wang, Franklin Fung, Hanyue Ding, Zhi-Jie Zheng, Differences in Incidence and Mortality Trends of Colorectal Cancer, Worldwide, Based on Sex, Age, and Anatomic Location. Clin Gastroenterol Hepatol 2021;19:955-966.e61. (Original Research; Impact Factor: 11.382, rank: 8/92 in Gastroenterology and Hepatology
  2. Martin CS Wong, Rungsun Rerknimitr, Khean Lee Goh, Takahisa Matsuda, Hyun-Soo Kim, Deng-Chyang Wu, Kai Chun Wu, Khay Guan Yeoh, Vui Heng Chong, Furqaan Ahmed, Jose D. Sollano, Jayaram Menon, Han-Mo Chiu, Jingnan Li, Jessica YL Ching, Joseph JY Sung. Development and Validation of the Asia-Pacific Proximal Colon Neoplasia Risk Score. Clin Gastroenteorol Hepatol 2021;19:119-127.e1 (Original Research; Impact Factor: 11.382, rank: 8/92 in Gastroenterology and Hepatology)