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Prof. Ye PENG

彭也教授

PhD Microbiome Science (HKU), MSc Biochemistry & Molecular Biology (SCUT), BEng Biopharmaceutical Engineering (SCUT)

Research Assistant Professor

Email: yepeng@cuhk.edu.hk

 

ORCID: 0000-0003-3791-2305

Scopus Author ID: 57218526006​

Academic Appointments

  • Editor, Cellular and Molecular Life Sciences

  • Guest Editor, Biomedicines

  • Review Editor, Frontiers in Microbiomes

  • Mentor, Fleming Fund Fellowships

Biography

Dr. Ye Peng is a microbiome scientist specializing in the gut microbiome’s role in early-life health and disease. He completed his PhD at the University of Hong Kong and received postdoctoral training at the Chinese University of Hong Kong, where his cohort studies revealed how perinatal exposures shape gut microbiota development and influence childhood obesity, food sensitization, immune responses to vaccines and colonization resistance against AMR bacteria. Dr. Peng’s interdisciplinary research integrates multi-omics, epidemiology, and machine learning to advance microbiome science and combat antimicrobial resistance. His long-term vision focuses on defining “healthy microbiomes” and translating discoveries into personalized therapies to improve health from early childhood to aging populations.

Research Interests

  • Multi-Omics studies on roles of microbiome in health and diseases 

  • Development of tools for microbiome and AMR science

Selected Publications

  1. Peng Y*, Zhu J*, Wang S*, Liu Y*, Liu X, DeLeon O, Zhu W, Xu Z, Zhang X, Zhao S, Liang S, Li H, Ho B, Ching JY, Cheung CP, Leung TF, Tam WH, Leung TY, Chang EB, Chan FKL, Zhang L#, Ng SC#, Tun HM#. A metagenome-assembled genome inventory for children reveals early-life gut bacteriome and virome dynamics. Cell Host Microbe. 2024 Dec 11;32(12):2212-2230.e8.

  2. Peng Y*, Tun HM*#, Ng SC, Wai HK, Zhang X, Parks J, Field CJ, Mandhane P, Moraes TJ, Simons E, Turvey SE, Subbarao P, Brook JR, Takaro TK, Scott JA, Chan FK, Kozyrskyj AL#. Maternal smoking during pregnancy increases the risk of gut microbiome-associated childhood overweight and obesity. Gut Microbes. 2024 Jan-Dec;16(1):2323234.

  3. Tun HM*, Peng Y*, Massimino L, Sin ZY, Parigi TL, Facoetti A, Rahman S, Danese S, Ungaro F#. Gut virome in inflammatory bowel disease and beyond. Gut. 2024 Jan 5;73(2):350-360.

  4. Peng Y*, Zhang L*, Mok CKP, Ching JYL, Zhao S, Wong MKL, Zhu J, Chen C, Wang S, Yan S, Qin B, Liu Y, Zhang X, Cheung CP, Cheong PK, Ip KL, Fung ACH, Wong KKY, Hui DSC, Chan FKL, Ng SC#, Tun HM#. Baseline gut microbiota and metabolome predict durable immunogenicity to SARS-CoV-2 vaccines. Signal Transduct Target Ther. 2023 Sep 25;8(1):373.

  5. Peng Y*, Chiu ATG*, Li VWY*, Zhang X, Yeung WL, Chan SHS#, Tun HM#. The role of the gut-microbiome-brain axis in metabolic remodeling amongst children with cerebral palsy and epilepsy. Front Neurol. 2023 Feb 27;14:1109469.

  6. Ng SC*, Peng Y*, Zhang L*, Mok CK, Zhao S, Li A, Ching JY, Liu Y, Yan S, Chan DLS, Zhu J, Chen C, Fung AC, Wong KK, Hui DS, Chan FK#, Tun HM#. Gut microbiota composition is associated with SARS-CoV-2 vaccine immunogenicity and adverse events. Gut. 2022 Jun;71(6):1106-1116.

  7. Peng Y*, Zhang D*, Chen T, Xia Y, Wu P, Seto WK, Kozyrskyj AL, Cowling BJ, Zhao J, Tun HM#. Gut microbiome and resistome changes during the first wave of the COVID-19 pandemic in comparison with pre-pandemic travel-related changes. J Travel Med. 2021 Oct 11;28(7):taab067.

  8. Tun HM*#, Peng Y*, Chen B, Konya TB, Morales-Lizcano NP, Chari R, Field CJ, Guttman DS, Becker AB, Mandhane PJ, Moraes TJ, Sears MR, Turvey SE, Subbarao P, Simons E, Scott JA, Kozyrskyj AL#. Ethnicity Associations With Food Sensitization Are Mediated by Gut Microbiota Development in the First Year of Life. Gastroenterology. 2021 Jul;161(1):94-106.

  9. Peng Y*, Liang S*, Poonsuk K*, On H, Li SW, Maurin MMP, Chan CH, Chan CL, Sin ZY, Tun HM#. Role of gut microbiota in travel-related acquisition of extended spectrum β-lactamase-producing Enterobacteriaceae. J Travel Med. 2021 Apr 14;28(3):taab022.

  10. Peng Y*, Tang S*, Wang D*, Zhong H, Jia H, Cai X, Zhang Z, Xiao M, Yang H, Wang J, Kristiansen K, Xu X, Li J#. MetaPGN: a pipeline for construction and graphical visualization of annotated pangenome networks. Gigascience. 2018 Nov 1;7(11):giy121.

Last Updated: 12 March 2025

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