Prof. Ngai Sze WONG
王艾斯教授

Prof. Ngai Sze WONG
BSSc (CUHK), M.Phil (CUHK), PhD (CUHK)
Assistant Professor
candy_wong@cuhk.edu.hk

Research Links

ORCID: 0000-0003-3788-8114

ResearcherID: A-3145-2012

Bio

Dr. Wong majored in Geography and Resources Management in her undergraduate days, and conducted research in the spatial epidemiology of methadone maintenance treatment utilization for her M.Phil study in The Chinese University of Hong Kong (CUHK). Her geographic information system (GIS) skills were further trained when she worked as a GIS assistant consultant in an environmental impact assessment company, and in an IT company which resells Google geo-products. She established her research skills and knowledge of infectious diseases and public health when she worked as a research assistant in Stanley Ho Centre for Emerging Infectious Diseases, CUHK, for around 4 years. She was also a part-time PhD student in School of Public Health, CUHK. Her doctoral study aimed at estimating HIV population viral load and simulating the impact of test-and-treat intervention on the HIV epidemic growth in Hong Kong through epidemic modelling. She later joined a joint China-US postdoc programme, working in South China-UNC STD Research Training Center in Guangzhou, and University of North Carolina at Chapel Hill in US. Her postdoctoral studies focused on the HIV linkage and retention in care, and syphilis epidemiology with the use of epidemic modelling and spatiotemporal analyses in South China.

 

She was the principal investigator (PI) of a few HIV research projects, such as HIV pre-exposure prophylaxis (PrEP) implementation study, chemsex engagement cross-sectional study, and cost-effectiveness analysis for latent TB infection screening strategies in people in HIV care. She is the PI of sexually transmitted infection (STI) epidemiological studies, and HBV and HCV epidemic modelling projects in Hong Kong. She has published more than 100 articles in peer-reviewed journals, and is currently a journal editorial board member of Infectious Diseases.

Research Interest

  • Epidemiology of infectious diseases, including HIV, Hepatitis B, Hepatitis C, sexually transmitted infections, Influenza, TB, dengue, and COVID-19
  • Application of spatial, temporal, social networking, and epidemic modelling to study epidemiology
  • Biomedical intervention strategies for HIV/STI epidemic control

Recent Funded Research Projects

  • Mycoplasma Genitalium Infection and Associated Antimicrobial Resistance among HIV-infected Male in Hong Kong. HMRF.
  • Mathematical Modelling Study of Hepatitis B Virus and Hepatitis C Virus Infection in Hong Kong and Economic Evaluation of Hepatitis B Screening Strategies. Department of Health.
  • Population burden of sexually transmitted infections and implication for intervention in Hong Kong. HMRF Commissioned Research on Control of Infectious Diseases.
  • The interrelationship between chemsex engagement and HIV biomedical prevention in MSM. Council for the AIDS Trust Fund.
  • A simplified approach to PrEP service delivery in real-world setting in Hong Kong. Council for the AIDS Trust Fund.
  • HIV epidemiology consultancy Hong Kong 2021 project. Department of Health.
  • Perception of pre-exposure prophylaxis (PrEP) use and its monitoring mechanism in men who have sex with men (MSM) – a qualitative study. Council for the AIDS Trust Fund.

Selected Publications

  1. Chan, C. P., Lee, S. S., Kwan, T. H., Wong, S. Y. S., Yeoh, E. K., & Wong, N. S.* (2024). Population Behavior Changes Underlying Phasic Shifts of SARS-CoV-2 Exposure Settings Across 3 Omicron Epidemic Waves in Hong Kong: Prospective Cohort Study. JMIR public health and surveillance, 10, e51498.
  2. Wong, N. S., Chan, D. P., Chung, S. L., Kwan, T. H., Lee, K. C., Kwan, C. K., & Lee, S. S. (2024). Self-sampled multi-anatomic site testing for uncovering the community burden of undiagnosed Chlamydia trachomatis and Neisseria gonorrhoeae infection in men who have sex with men. Infection, 52(2), 491–502.
  3. Wong, N. S., Chan, D. P., Kwan, T. H., Lui, G. C., Lee, K. C., & Lee, S. S. (2024). Dynamicity of HIV Pre-exposure Prophylaxis Usage Pattern and Association with Executed Adherence in MSM: An Implementation Study in Hong Kong. AIDS and behavior, 28(4), 1327–1344.
  4. Wong, N. S.*, Tang, W., Miller, W. C., Ong, J. J., & Lee, S. S. (2024). Expanded HIV testing in non-key populations – the neglected strategy for minimising late diagnosis. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 138, 38–40.
  5. Wong, N. S., Chan, D. P. C., Poon, C. M., Chan, C. P., Lau, L. H. W., Yeoh, E. K., & Lee, S. S. (2023). Hepatitis B burden and population immunity in a high endemicity city – a geographically random household epidemiology study for evaluating achievability of elimination. Epidemiology and infection, 151, e22.
  6. Wong, N. S., Chan, D. P., Chan, C. P., Poon, C. M., Wong, G. L., Wong, V. W., & Lee, S. S. (2022). Point-of-care hepatitis C reflex testing and treatment referral in methadone clinic settings in Hong Kong-a pilot study. IJID regions, 5, 8–12.
  7. Wong, N. S.(co-first), Lee, S. S., Chan, D. P. C., Li, T. C. M., Ho, T. H. Y., Luk, F. W. L., Chow, K. M., Tso, E. Y. K., Yeoh, E. K., Wong, S. Y. S., Hui, D. S. C., & Lui, G. C. Y. (2022). Trajectory patterns of SARS-CoV-2 neutralising antibody response in convalescent COVID-19 patients. Communications medicine, 2, 53.
  8. Wong, N. S., Wong, B. C. K., Chan, J. M. C., Wong, K. H., Tsang, O. T. Y., Mok, C. K. P., Hui, D. S. C., Lee, S. S., & Chan, D. P. C. (2022). Surrogate neutralization responses following severe acute respiratory syndrome coronavirus 2 vaccination in people with HIV: comparison between inactivated and mRNA vaccine. AIDS (London, England), 36(9), 1255–1264.
  9. Chan, C. P., Lee, S. S., &Wong, N. S.* (2021). Adherence of nurses to annual seasonal influenza vaccination over a 5-year period. The Journal of hospital infection, 112, 6–15.
  10. Wong, N. S., Lee, S. S., Kwan, T. H., & Yeoh, E. K. (2020). Settings of virus exposure and their implications in the propagation of transmission networks in a COVID-19 outbreak. The Lancet regional health. Western Pacific, 4, 100052.
  11. Wong, N. S., Leung, C. C., & Lee, S. S. (2020). Abrupt Subsidence of Seasonal Influenza after COVID-19 Outbreak, Hong Kong, China. Emerging infectious diseases, 26(11), 2753–2755.
  12. Wong, N. S., Kwan, T. H., Lee, K., Lau, J., & Lee, S. S. (2020). Delineation of chemsex patterns of men who have sex with men in association with their sexual networks and linkage to HIV prevention. The International journal on drug policy, 75, 102591.
  13. Wong, N. S., Chan, K., Wong, B., Leung, C. C., Chan, W. K., Lin, A., Lui, G., Mitchell, K. M., & Lee, S. S. (2019). Latent Tuberculosis Infection Testing Strategies for HIV-Positive Individuals in Hong Kong. JAMA network open, 2(9), e1910960.
  14. Wong, N. S., Leung, C. C., Chan, K., Chan, W. K., Lin, A., & Lee, S. S. (2019). A longitudinal study on latent TB infection screening and its association with TB incidence in HIV patients. Scientific reports, 9(1), 10093.