BMC Psychiatry, 24(1), 400.
Mak, B. S. W., Zhang, D., Powell, C. L. Y. M., Leung, M. K. W., Lo, H. H. M., Yang, X., Yip, B. H. K., Lee, E. K. P., Xu, Z., & Wong, S. Y. S.* (2024).
基層醫療臨床試驗小組
作為區內基層醫療研究的領先樞紐，賽馬會公共衞生及基層醫療學院很榮幸成立基層醫療臨床試驗小組（PCCTU），以實現以下目標：
- 致力透過高質素、循證為本的臨床試驗，應對迫切的健康挑戰，改善病人健康成果，並為醫療政策提供實證依據；
- 透過嚴謹的研究推動基層醫療的知識發展與創新，同時促進醫療專業人員、研究人員與政策制定者之間的合作；
- 推動循證方案，提升個人及社區的健康與福祉。
加入我們
PCCTU配備先進的基礎設施，由一支涵蓋臨床試驗、生物統計學及基層醫療等多領域的專業團隊組成。我們誠邀研究人員、醫療專業人士及社區成員加入我們的行列，攜手推動循證實踐，透過具影響力的研究改善病人生活。
如欲了解更多有關PCCTU的資訊或探索合作機會，歡迎聯絡我們：
地址：香港新界沙田威爾斯親王醫院公共衞生學院大樓202室
我們的團隊
重點範疇
- 精神健康
- 在基層醫療環境中，開發及評估針對精神健康問題的早期識別、介入及管理的新方法。
- 探索將精神健康服務融入日常基層醫療的可行性，以減少污名化並提升服務的可及性。
- 痛症
- 研究創新策略以管理慢性痛症，包括肌肉骨骼痛、神經性痛症及廣泛性慢性痛症，從而提升生活質素。
- 評估非藥物治療方法（如數碼健康工具及運動治療）在痛症管理方面的成效。
- 高血壓
- 進行臨床試驗以優化高血壓的管理與預防，重點包括個人化護理及生活方式調整。
- 評估流動健康科技及以病人為本的介入措施對血壓控制的影響。
- 疾病預防
- 推動初級預防策略，包括生活方式介入及社區為本的計劃，以減輕慢性疾病的負擔。
- 探索提升疫苗接種率及公眾健康素養的創新方法。
臨床試驗
現正招募中的臨床試驗
| 1 | The efficacy of an online exercise intervention for improving depressive symptoms among patients with subthreshold depression in primary care: a randomized controlled trial
Grant/Fund: HMRF #21220291 PI: Prof. Samuel Wong |
| 2 | Can TElemedicine system replace doctor consultations to Achieve non-inferior blood pressure in patients with Controlled Hypertension (TEACH)? a randomised controlled trial and cost-minimization analysis
Grant/Fund: HMRF #21220241 PI: Prof. Eric Lee |
| 3 | Effectiveness and mechanisms of isometric resistance exercise to reduce blood pressure in a Chinese population: a randomized-controlled trial
Grant/Fund: GRF #14108224 PI: Prof. Eric Lee |
最近完成的臨床試驗
| 1 | Effects of mindfulness-based cognitive therapy for adults with post-traumatic stress disorder symptoms in primary care: a randomised controlled trial Grant/Fund: GRF #14609021 PI: Prof. Samuel Wong |
| 2 | The effects of mindfulness-based intervention for loneliness on older adults: a randomised controlled trial Grant/Fund: GRF #14609020 PI: Prof. Samuel Wong |
| 3 | Combining mind body physical exercise, cognitive training, and nurse-led risk factor modification to enhance cognition among older adults with mild cognitive impairment: a randomized controlled trial Grant/Fund: HMRF #16170421 PI: Prof. Samuel Wong |
| 4 | The feasibility and effects of mindfulness-based relapse prevention (MBRP) on reducing craving and addictive behaviour in local adults with substance abuse disorders Grant/Fund: Beat Drug Fund #180056 PI: Prof. Samuel Wong |
| 5 | Dextrose Prolotherapy injection improves dynamic postural balance and reduces number of recurrent sprains in Chronic Ankle Instability: A one-year randomized placebo-controlled trial PI: Prof. Regina Sit |
| 6 | Feasibility and acceptability of mindfulness-based stress reduction program on patients with nocturnal hypertension: A pilot randomized controlled trial Grant/Fund: HMRF #20210541 PI: Prof. Eric Lee |
| 7 | Home blood pressure during night-time sleep as a better treatment target for patients with hypertension: a proof-of-concept randomized controlled trial Grant/Fund: HMRF #18190461 PI: Prof. Eric Lee |
研究出版物
Journal of Pharmaceutical Policy and Practice. 2025 Dec 31;18(1):2463435.
Lee EKP, Wang S, Yip BH, Yu EY, Leung SY, Han J, Choi YK, Chow KF, Chung WH, Yan BP, Mihailidou AS.
Journal of the American Medical Directors Association. 2025;26(1)
Lo HHM, Fong PYH, Wang B, Fung CL-C, Wong SY-S, Sit RWS*.
JMIR Serious Games 12 (2024/9/27 2024): e52563. (IF 3.8, rank 24/174 Health Care Sciences & Services, JCR 2023)
Lo, Hermione Hin Man, Marques Ng, Pak Yiu Hugo Fong, Harmony Hoi Ki Lai, Bo Wang, Samuel Yeung-shan Wong, and Regina Wing Shan Sit*.
Chronic Dis Transl Med. 2024 Mar;10(1):12-21. doi: 10.1002/cdt3.89. eCollection 2024 Mar. Review. PubMed PMID: 38450300; PubMed Central PMCID: PMC10914011.
Xiong Y, Huo Z, Wong SYS, Yip BHK*.
Psychotherapy and Psychosomatics, 92(6), 379–390.
Wong, S. Y. S.,* Chan, S. K. C., Yip, B. H. K., Wang, W., Lo,, H. H. M., Zhang, D., & Bögels, S., M. (2024).
Journal of Medical Systems. 2023 Mar 11;47(1):34.
Wang S, Leung M, Leung SY, Han J, Leung W, Hui E, Mihailidou AS, Kam-Fai Tsoi K, Chi-Sang Wong M, Wong SY, Lee EKP.
Mindfulness 2023.
Li X, Lau ENS, Chan SKC, Lam TP, Cheng JCY, Lee EKP, Wong SYS, YIP BHK*.
Mindfulness, 14(1), 50-65.
Zhang, D., Tsang, K.W.K., Duncan, L.G., Yip, B.H.K., Chan, D.C.C., Lee, E.K.P., Gao, T.T., Tam, W.H., Lam, K.Y., Tong, W.H., Bardacke, N., Wong, S.Y.S.* (2023).
Cost Effectiveness and Resource Allocation 20. 2022;19.
Huo Z, Lin J, Bat BKK, Chan TK, Yip BHK, Tsoi KKF.
Value in Health. 2021 Dec;24(12):1853-1862.
Huo Z, Chan JY, Lin J, Bat BK, Chan TK, Tsoi KK, Yip BH*.
American Journal of Hypertension. 2021 Jul 1;34(7):753-9.
Lee EKP, Zhang DD, Yip BH, Cheng J, Hui SS, Yu EY, Leung M, Chu WC, Mihailidou AS, Wong SY.
BMJ Open, 8(11), e022514.
Chan, S. K. C., Zhang, D., Bögels, S. M., Chan, C. S., Lai, K. Y. C., Lo, H. H. M., Yip, B. H. K., Lau, E. N. S., Gao, T. T., & Wong, S. Y. S.* (2018).
Scientific Reports. 2018;8(1):1–9.
Yip BHK*, Lee EKP, Sit RWS, Wong C, Li X, Wong ELY, Wong MCS, Chung RYN, Chung VCH, Kung K, Wong SYS.
Scientific Reports, 8(1), 6609.
Wong, C., Yip, B. H., Gao, T., Lam, K. Y. Y., Woo, D. M. S., Yip, A. L. K., Chin, C. Y., Tang, W. P. Y., Choy, M. M. T., Tsang, K. W. K., Ho, S. C., Ma, H. S. W., & Wong, S. Y. S.* (2018).
Annals of Family Medicine, 16(2), 111–119.
Wong, S. Y. S.*, Sun, Y. Y., Chan, A. T. Y., Leung, M. K. W., Chao, D. V. K., Li, C. C. K., Chan, K. K. H., Tang, W. K., Mazzucchelli, T., Au, A. M. L., & Yip, B. H. K. (2018).
JAMA Oncol. 2017 Sep 1;3(9):1281-128
Wong MCS*, Ching JYL, Lam TYT, Ng SKC, Wong JCT, Wu JCY, Chan FKL.
Psychotherapy and Psychosomatics, 86(4), 241–253.
Wong, S. Y.*, Zhang, D. X., Li, C. C., Yip, B. H., Chan, D. C., Ling, Y. M., Lo, C. S., Woo, D. M., Sun, Y. Y., Ma, H., Mak, W. W., Gao, T., Lee, T. M., & Wing, Y. K. (2017).
British Journal of Psychiatry, 209(1), 68–75.
Wong, S. Y.*, Yip, B. H., Mak, W. W., Mercer, S., Cheung, E. Y., Ling, C. Y., Lui, W. W., Tang, W. K., Lo, H. H., Wu, J. C., Lee, T. M., Gao, T., Griffiths, S. M., Chan, P. H., & Ma, H. S. (2016).
Eur Heart J. 2015 Oct 7;36(38):2598-607.
Epub 2015 Aug 11. PMID: 26264550.
Wong MC*, Wang HH, Kwan MW, Fong BC, Chan WM, Zhang DX, Li ST, Yan BP, Coats AJ, Griffiths SM.