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Dr. Regina Wing-Shan SIT
薛詠珊醫生
Dr. Regina Wing-Shan SIT
MD (CUHK), MBBS (HK), DCH (HK), DPD (Cardiff), PDip Community Geriatrics (HK), DipMed (CUHK), FRACGP, FHKCFP, FHKAM (Family Medicine)
Associate Professor (Clinical)
reginasit@cuhk.edu.hk
Research Links
Academic Appointments
- Director, Primary Care Clinical Trial Unit, JCSPHPC
Bio
Dr. Regina Sit is an Associate Professor (Clinical) at the Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong. She obtained her MBBS degree from the University of Hong Kong and subsequently became a Family Medicine Specialist. Alongside her specialist training, she developed advanced expertise in pain management and is a Certified Interventional Pain Sonologist with the World Institute of Pain. Dr. Sit also completed her Doctor of Medicine (MD) research degree.
As a clinician-scientist, Dr. Sit focuses her clinical and research work on chronic musculoskeletal pain in primary care. She has an established publication record with studies published in leading primary care, pain, and orthopaedic journals, including Annals of Family Medicine, British Journal of General Practice, Pain, and Osteoarthritis and Cartilage.
Driven by her passion for advancing clinical trials in primary care, Dr. Sit now serves as the Director of the School’s Primary Care Clinical Trials Unit, where she aims to extend high-calibre clinical research into the community and develop the Unit into a leading hub for primary care clinical trials in Asia.
Research Interest
- Musculoskeletal Pain Medicine
- Randomized Clinical Trials
Recent Funded Research Projects
- Lifestyle Medicine for Chronic Musculoskeletal Pain in Older Adults- a pragmatic randomized controlled trial (Private Donation)
- Development of local adaptable acupuncture indications for patients with musculoskeletal and connective tissue diseases in Hong Kong primary care settings: Recommendations guided by the GRADE ADOLOPMENT approach (Chinese Medicine Development Fund )
- Risk Assessment and Management Program (RAMP) on knee osteoarthritis in primary care – a one-year pragmatic randomized controlled trial (Health and Medical Research Fund)
- Gut Microbiota in Adults with Chronic Wide-Spread Pain: A pilot case-control study (Peter Hung Pain Research Institute)
Selected Publications
- Ho, L., C. N. T. Lai, H. Chen, S. W. Law, E. C. L. Yu, F. P. Y. Lam, Y. C. Cheung, I. X. Wu, S. Y. S. Wong and R. W. S. Sit* (2025). “Systematic review of clinical practice guidelines on acupuncture for chronic musculoskeletal pain.” BMC Complementary Medicine and Therapies 25(1): 322
- Lo HHM, Fong PYH, Wang B, Fung CL-C, Wong SY-S, Sit RWS*. Clinical Efficacy of Virtual Reality Cave Automatic Virtual Environments (CAVE) for Chronic Musculoskeletal Pain in Older Adults: A Randomized Controlled Trial. Journal of the American Medical Directors Association. 2025;26(1)
- Butler CC, Mash R, Gobat N, Little P, Makasa M, Makwero M, Mills EJ, Sit RW-S, Bachmann MO. Democratising clinical trials research to strengthen primary health care. The Lancet Global Health 2025;13(4):e749-e758.
- Shi, Jenny Lin-Hong, and Regina Wing-Shan Sit*. “Impact of 25 Years of Mobile Health Tools for Pain Management in Patients with Chronic Musculoskeletal Pain: Systematic Review.” Journal of Medical Internet Research 26 (2024): e59358. (IF 5.8, rank 9/174 Health Care Sciences & Services, JCR 2023)
- Lo H, Zhu M, Zou Z, Wong C, Lo S, Chung V, Wong S, Sit R*. Immersive and Non-immersive Virtual Reality–Assisted Active Training in Chronic Musculoskeletal Pain: Systematic Review and Meta-Analysis. J Med Internet Res 2024;26:e48787 (DOI: 10.2196/48787) (IF 5.8, rank 9/174 Health Care Sciences & Services, JCR 2023)
- Mengting Zhu; Dong Dong; Hermione Hin-man Lo; Samuel Yeung-shan Wong; Phoenix Kit-han Mo; Regina Wing Shan Sit*. Patient preferences in the treatment of chronic musculoskeletal pain: A systematic review of discrete choice experiments. PAIN, 10.1097, 2022.
- (IF 7.926, rank 5/35 in Anesthesiology, JCR 2021)
- Sit, Regina Wing Shan*, Shirley Yue Kwan Choi, Bo Wang, Dicken Cheong Chun Chan, Dexing Zhang, Benjamin Hon Kei Yip, and Samuel Yeung Shan Wong. “Neuromuscular Exercise for Chronic Musculoskeletal Pain in Older People: A Randomised Controlled Trial in Primary Care in Hong Kong.” British Journal of General Practice 71, no. 704 (2021): e226-e236.
- Regina Sit WS*, Ricky Wu WK, D Rabago, Kenneth D Reeves, Dicken Chan CC, Benjamin Yip HK, Vincent Chung CH, Samuel Wong YS. Efficacy of Intra-Articular Hypertonic Dextrose (Prolotherapy) for Knee Osteoarthritis: A Randomized Controlled Trial. The Annals of Family Medicine 2020;18(3):235-242.
- Sit RWS*, Chan KKW, Zou D, Chan DCC, Yip BHK, Zhang DD, Chan YH, Chung VCH, Reeves KD, Wong SYS. Clinic-Based Patellar Mobilization Therapy for Knee Osteoarthritis: A Randomized Clinical Trial. Annals of Family Medicine. 2018; 16: 521-529.