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学院教职员

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彭也教授

Prof. Ye PENG

PhD Microbiome Science (HKU), MSc Biochemistry & Molecular Biology (SCUT), BEng Biopharmaceutical Engineering (SCUT)

研究助理教授

电邮: yepeng@cuhk.edu.hk

 

ORCID: 0000-0003-3791-2305

Scopus Author ID: 57218526006

学术委任

  • Cellular and Molecular Life Sciences编辑

  • Biomedicines客座编辑

  • Frontiers in Microbiomes审稿编辑

  • Fleming Fund Fellowships导师

个人简介

彭也博士是一位专注于肠道微生物群在早期生命健康与疾病中角色的微生物群科学家。他在香港大学完成博士学位，并在香港中文大学接受博士后培训，他的队列研究揭示了围产期暴露如何塑造肠道微生物群的发展并影响儿童肥胖、食物敏感，对疫苗的免疫反应以及对抗抗生素耐药性细菌的定植抵抗力。彭博士的跨学科研究结合了多组学、流行病学和机器学习，以推进微生物群科学并抗击抗生素耐药性。他的长期愿景是明确定义「健康的微生物群」，并将发现转化为个性化疗法，以改善从儿童到老龄人口的健康。

研究方向

  • 微生物组在健康与疾病中作用的多组学研究

  • 开发微生物组及抗菌素抗药性相关的科学研究工具

部份学术文章

  1. Peng Y*, Zhu J*, Wang S*, Liu Y*, Liu X, DeLeon O, Zhu W, Xu Z, Zhang X, Zhao S, Liang S, Li H, Ho B, Ching JY, Cheung CP, Leung TF, Tam WH, Leung TY, Chang EB, Chan FKL, Zhang L#, Ng SC#, Tun HM#. A metagenome-assembled genome inventory for children reveals early-life gut bacteriome and virome dynamics. Cell Host Microbe. 2024 Dec 11;32(12):2212-2230.e8.

  2. Peng Y*, Tun HM*#, Ng SC, Wai HK, Zhang X, Parks J, Field CJ, Mandhane P, Moraes TJ, Simons E, Turvey SE, Subbarao P, Brook JR, Takaro TK, Scott JA, Chan FK, Kozyrskyj AL#. Maternal smoking during pregnancy increases the risk of gut microbiome-associated childhood overweight and obesity. Gut Microbes. 2024 Jan-Dec;16(1):2323234.

  3. Tun HM*, Peng Y*, Massimino L, Sin ZY, Parigi TL, Facoetti A, Rahman S, Danese S, Ungaro F#. Gut virome in inflammatory bowel disease and beyond. Gut. 2024 Jan 5;73(2):350-360.

  4. Peng Y*, Zhang L*, Mok CKP, Ching JYL, Zhao S, Wong MKL, Zhu J, Chen C, Wang S, Yan S, Qin B, Liu Y, Zhang X, Cheung CP, Cheong PK, Ip KL, Fung ACH, Wong KKY, Hui DSC, Chan FKL, Ng SC#, Tun HM#. Baseline gut microbiota and metabolome predict durable immunogenicity to SARS-CoV-2 vaccines. Signal Transduct Target Ther. 2023 Sep 25;8(1):373.

  5. Peng Y*, Chiu ATG*, Li VWY*, Zhang X, Yeung WL, Chan SHS#, Tun HM#. The role of the gut-microbiome-brain axis in metabolic remodeling amongst children with cerebral palsy and epilepsy. Front Neurol. 2023 Feb 27;14:1109469.

  6. Ng SC*, Peng Y*, Zhang L*, Mok CK, Zhao S, Li A, Ching JY, Liu Y, Yan S, Chan DLS, Zhu J, Chen C, Fung AC, Wong KK, Hui DS, Chan FK#, Tun HM#. Gut microbiota composition is associated with SARS-CoV-2 vaccine immunogenicity and adverse events. Gut. 2022 Jun;71(6):1106-1116.

  7. Peng Y*, Zhang D*, Chen T, Xia Y, Wu P, Seto WK, Kozyrskyj AL, Cowling BJ, Zhao J, Tun HM#. Gut microbiome and resistome changes during the first wave of the COVID-19 pandemic in comparison with pre-pandemic travel-related changes. J Travel Med. 2021 Oct 11;28(7):taab067.

  8. Tun HM*#, Peng Y*, Chen B, Konya TB, Morales-Lizcano NP, Chari R, Field CJ, Guttman DS, Becker AB, Mandhane PJ, Moraes TJ, Sears MR, Turvey SE, Subbarao P, Simons E, Scott JA, Kozyrskyj AL#. Ethnicity Associations With Food Sensitization Are Mediated by Gut Microbiota Development in the First Year of Life. Gastroenterology. 2021 Jul;161(1):94-106.

  9. Peng Y*, Liang S*, Poonsuk K*, On H, Li SW, Maurin MMP, Chan CH, Chan CL, Sin ZY, Tun HM#. Role of gut microbiota in travel-related acquisition of extended spectrum β-lactamase-producing Enterobacteriaceae. J Travel Med. 2021 Apr 14;28(3):taab022.

  10. Peng Y*, Tang S*, Wang D*, Zhong H, Jia H, Cai X, Zhang Z, Xiao M, Yang H, Wang J, Kristiansen K, Xu X, Li J#. MetaPGN: a pipeline for construction and graphical visualization of annotated pangenome networks. Gigascience. 2018 Nov 1;7(11):giy121.

Last Updated: 12 March 2025

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